Tuesday, March 21, 2017

Off To The Races

Today will be my fourth treatment. I am a little nervous because the dose will be increased and the last trip was pretty intense. I know that my doc is there to keep me balanced and can relieve any overwhelming feelings so I will go in with a positive attitude, do a little mindfulness meditation and go with the flow. I am as ready as I can be. More post treatment.

If you are curious about how this helps your brain, here is a very simple explanation:

Ketamine is completely different from SSRIs, tricyclics, MOAI inhibitors, benzos, or any other antidepressant or anti-anxiety medication.  The exact mechanism that causes ketamine to relieve depression is still under study, and is quite complex.  In short, when ketamine is administered in a very precise way it triggers a cascading sequence of events in the brain, which ultimately results in the re-growth of neurons that previously died off.  It is thought by some researchers that prolonged exposure to stress causes these neurons die off in the first place, resulting in depression, but ketamine causes them to rapidly re-grow within hours, relieving the depressive symptoms.  This is an oversimplification of a very complex topic, and the latest research hints there may be several other mechanisms involved that also play important roles.  Elsewhere on this site you’ll find more in-depth discussion, as well as a research database.

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